Among the oncological diseases in the USA, provoked by human papilloma virus (HPV), the frequency of oropharyngeal cancer exceeded frequency of cervical cancer.
The CDC (American Center for Disease Control and Prevention) published a report on the incidence of HPV-associated cancers, which covers the period from 1999 to 2015. The source of information was the register of oncological diseases, in which data are presented about 97.8% of the US population.
Total number of cases of HPV-associated cancers in 1999 was 30,115, in 2015 - 43,371 cases. In the period of 16 years, the average annual decrease in the morbidity of cervical cancer was 1.6%, squamous cell carcinoma of the vagina - 0.6%. However, there was an increase in the morbidity of oropharyngeal squamous cell cancer among men (+ 2.7%) and women (+ 0.8%) annually, anal squamous cell cancer in men (+ 2.1%) and women (+ 2.9%), vulvar cancer (+ 1.3%). The morbidity of penile cancer remained without changes.
In 2015, oropharyngeal squamous cell carcinoma was the most common HPV-associated cancer (15 479 cases among men and 3 438 among women).
Researchers note that HPV is the most common sexually transmitted infection in the United States. Changes in sexual behavior in a population could be one of the reasons for the change in the morbidity of HPV-associated cancer: unprotected oral and anal sex are risk factors for the transmission of HPV. In addition, unlike cervical cancer, there are no screening companies in the United States aimed at the early detection of oropharyngeal cancer and the conditions preceding it.